Award Winners
Award Winners
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 WWE CLASSIC SUPERSTARS HULK HOGAN TOYFARE 1 OF 3000 MOC US $35.98
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Itanium Alliance Innovation Award winners announced 08 with 5 million - the server, Itanium, corpora by hi joiney
Itanium? Solutions Alliance today announced the second annual Itanium Solutions Alliance Innovation Award. This year's winners are: the University of Houston bioinformatics research team was "Human Innovation Award"; Protégésoft was "Enterprise Business Application Award"; S7 Software was "Entrepreneurial Innovation Award." This global awards program that recognizes those who through Intel ? Itanium? Processor technology to solve complex humanitarian, business and entrepreneurship, innovation challenges and achievements. Winners each receive a sum of 50,000 U.S. dollars in cash rewards, but also their choice to donate money to a charity. Itanium Solutions Alliance executive director JoanJacobs said: "The winners and finalists solution clearly shows the Itanium? Solution relative to the higher cost of a mainframe, in practical application has significant value. They The story clearly shows that Intel Itanium technology applications for solving problems of mission critical computing environments play a significant role. Participants broad categories, which were selected from each category a winner far from easy. Itanium 3 Solutions Alliance would like to extend my warm congratulations to the winners! " Human contribution to the Innovation Award winners, the University of Houston researchers Dr. Yuriy Fofanov Dr. LennartJohnsson and his research team developed an application using high-performance computing solutions and the latest genome sequencing technology to identify and monitor the microbial gene diversity. The group's mission is to study global warming, human activity and toxic waste, in order to protect humans and other organisms and the environment against the harmful greenhouse gases, and Itanium systems was that they needed to advance the calculation of power tools. Bioinformatics Laboratory of the University of Houston Dr. Fofanov director, said: "Intel's Itanium processor, a powerful high-performance computing capabilities will enable scientists to enhance understanding of the micro-organisms, which is an indispensable factor in our study, important because we need to analyze genetic information. With Itanium systems Memory Bandwidth, we can operate the necessary genetic information, special data structure stored. In addition, the Itanium system, high availability to help us launch a new research project to promote the human environment, public health and safety, sustainable energy and other research advances. " "Enterprise Business Application" award winners to use the Intel Itanium architecture Protégésoft company replaced the original customer outdated and cumbersome system to give full play to the availability of powerful Itanium systems. Protégésoft developed FinancialPortfolioBuilder (FPB), a run on four-way Intel Itanium processor HP Integrity Server The comprehensive financial investment system. FPB supports a variety of portfolio management functions, including account settings, account maintenance, investment in distribution, monitoring and dynamic re-calculation, reporting and so on, all functions in one unified platform. For financial institutions, FPB can be re-counted within minutes thousands of customer accounts, not only can optimize risk and return risk, but also lower cost, higher performance to provide even better customer service. Using the tool, the investment banking clients access to more than 22% compound annual returns on investment, enhance efficiency than traditional methods nearly 3 million times. Protégésoft KumaranPillai CEO, said: "Itanium chip and platform with outstanding reliability and powerful features, its capacity to meet our requirements, giving us great help. Itanium flexible and scalable architecture improve the return on investment, so investment banks can be processed within minutes thousands of customer accounts. " S7 Software Solutions Company with a line of 200 million Software Code ported to Intel Itanium architecture unique projects to receive "Entrepreneurial Innovation" award. The project target is a "Fortune" hundred companies to support financial institutions processing, mortgage loan processing and other services, products, trading systems. With a shorter response time, higher availability and flexible scalability, Itanium platform, the solution to the migration problem of the ideal choice. S7 Software Solutions PhanirajRaghavendra software architect, said: "By the application engine customers to migrate to Intel Itanium architecture, we help our clients fully exploit the Itanium system scalability and performance advantages, including shorter trading hours, security, 24-hour processing and a wide range of software environments. Innovation Award this year by a panel of 11 industry experts. You judge according to level of difficulty, achieved results and to assess candidates for originality. Candidates can only apply for one of three groups and asked demonstrate the following criteria: "Application" of human innovation and contribution to the "award must demonstrate through scientific research, social improvements or other humanitarian work effectively demonstrated its profound impact on humans; "Application" Enterprise Business Application "award must prove hard business results, such as reducing costs and improving return on investment, or soft business impact, including customer satisfaction and new product development; "" Entrepreneurial Innovation "Award, for the last fiscal year the total income of less than 25 million U.S. dollars of private enterprise, designed to reward those who through IT consolidation, increased ROI, increased customer satisfaction and new product development areas of deployment of Itanium systems and innovative applications to achieve tangible results.
About the Author
We are high quality suppliers, our products such as China Optical Multiplexer , Fiber Optic Multiplexer for oversee buyer. To know more, please visits .
NRDC's 2012 Growing Green Award Winners' Film
Yankees Starting
Yankees Starting
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 T MUNSON Y BERRA 98 EDITION STARTING LINEUP SPORTS SUPERSTAR COLLECTIBLES NIB US $4.49
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Recognizing American Patriotic Music through "Yankee Doodle" & "America the Beautiful" by Miguel Carlos
Patriotic music encourages feelings of national unity. They can come in the form of national songs, hymns and even military themes. Below are two examples of popular patriotic songs in the US.
"Yankee Doodle"
Who among us have not heard of this song? It s not only a popular children's song, it is also one of America's patriotic songs. As a matter of fact, it is the state song of Connecticut.
The problem with the song is that despite its popularity, there are those who scrutinize it for the way it made fun of American troops. Thus, this song still became a part of American patriotism.
We can trace the origin of this song to old English folk music. It emerged prior to the American Revolution. It is how the British mocked American soldiers. This is how the term "yankee" came about as a negative term for the Americans. For "doodle", the term implies "simpleton" or "fool".
With regards to its inclusion in the American Revolution, when the Americans or "Yankees" began taking the British into the Revolution, they were also able to take command over this song. They started singing it proudly as a way to taunt English soldiers.
"America the Beautiful"
This is an American folk song that is often referred to as the national hymn of the US. This piece was adapted from Katharine Lee Bates, a Wellsely College English professor. She wrote in the year 1893 during her trip to Colorado. It mentions the beauty of the country she is traveling to. According to her, she got her inspiration from her visit to Pike's Peak.
The original version of this piece, only had four verses. After a while, they expanded it to eight verses and revised the lyrics. It was used by The Congregationalist to commemorate Independence Day in the year 1895. It was Samuel Ward, a New Jersey composer who gave music to the poem. A combination of both the poem and the music was first heard in 1910.
Though there was talk that "America the Beautiful" may replace "The Star Spangled Banner", there's no indication that this would even happen - nor if it is even considered. Still, the song projects the physical beauty and breadth of the United States.
About the Author
There are more examples of American <a href="<http://www.patrioticmusic.org>">patriotic music and other patriotic songs from other countries at PatrioticMusic.Org.
New York Yankees Starting Lineup 5-12-12
Doubles Slu
Doubles Slu
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Spinning Reels of the Modern Fishing Tackle Industry by Vien Menguy
The Mitchell Blade ALU 4500 Spinning reel is one of the newest additions of to the innovative yet simple fishing tackle industry today. This rod considers its high performance corrosion resistant (HPCR) ball bearings as its most important design. Rugged aluminum is the material used to create the body and rotor design of this rod and reel system. This model is considered as one of those with the best designs in the industry at present because of these features.
As already mentioned, one of the greatest innovations of this reel and rod system is its reel's ball bearings which are high performance corrosion resistant. The five ball bearings including the extra one is created and not merely coated with HPCR material so this reel can survive high pressure. Another plus factor is the reel's ability to run in dry and wet conditions without any loss in performance or efficiency. The bearings of this fishing tackle, moreover, are very low maintenance and saltwater resistant so it is truly the perfect tool for hardcore anglers.
The spool utilized on the spinning reel of this fishing tackle is double anodized. Anodization can be described as an electrochemical process of strengthening and hardening aluminum twice in order for the material in the fishing equipment to have high tensile strength and efficiency during stressful conditions. The power knob which is used to control the reel can be bought in sizes sixty and fifty and it also has an extra aluminum spool.
Strength is not the only glowing feature of this fishing tackle. The retrieve system of this spinning reel can both be used for left and right hand. There is also an anti-twist titanium line roller and a machined aluminum handle which provides precision as well as reliability during performance. Titanium is a special material that is only commonly used on high performance machines like Formula One cars and aircrafts for example. Therefore, users can expect this model to perform well even during difficult situations because this metal is integrated on its rod. Saltwater conditions are also properly handled by this model because of the stability that its anti-reverse system offers.
The design of this fishing tackle reel is built out of rust free aluminum. Despite its heavy duty capabilities, it only weighs in at a meager 373 grams. It has one of the highest retrieve ratio (6.2:1) among the rods on its same class and it can also carry 300 meters of 0.25 test line with ease. Moreover, often overlooked on this fishing tackle is its effective front drag system which offers the users smooth and slow pulling of the line without experiencing any jerky movements.
The Mitchell fishing tackle line was first created in France during the 1940s but shortly became one of the leading brands of the fishing magnate Pure Fishing. At present, the brand is considered equal to other brands like Fenwick, Berkley, and Abu Garcia. Ever since it was created, the brand has successfully continue its legacy of providing top quality products to various levels of anglers specifically to those who want to improve their rod's spinning technology. Blade SLU 450 is truly a model that you will never go wrong with.
About the Author
I have been fishing since i was 9 years old and absolutely nothing relaxes me more. To get the best money saving deals on fishing tackle throughout the uk i recommend KeensTackleandguns. Their friendly staff are extremely knowledgeable on everything relevant to fishing and are always very helpful. Take a look at their online fishing tackle store for more details or call 01656 722448.
SLU Shannon Murphy/Elizabeth Geer vs. Nazareth
Deion Sanders
Deion Sanders
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Atlanta Falcons by Jessydsouza
With three straight winning seasons and a pair of playoff appearances since 2008, the Atlanta Falcons are building a special force heading into the 2011 campaign. Atlanta Falcons tickets are moving quickly, as a winning culture is being established for the franchise.
Atlanta Falcons Tickets: Franchise History
In 1966, the Atlanta Falcons became the first NFL franchise to be based in the southeast. As an expansion team, it took time for the Falcons to build a competitive team. Atlanta reached the postseason for the first time in 1978.
During the sixties and seventies, linebacker Tommy Nobis, defensive lineman Claude Humphrey, center Jeff Van Note and quarterback Steve Bartkowski were among the star players for the Falcons.
In 1980, Atlanta won its first division title with a 12-4 record. In the eighties and early nineties, running back Gerald Riggs and defensive back Deion Sanders were Atlanta's top performers.
After playing at Atlanta's Fulton-County Stadium from 1966-91, the Falcons moved into its current home, which is the Georgia Dome, in 1992.
Atlanta's Super Bowl Season
The 1998 season marked the highpoint for the franchise. Following an outstanding 14-2 regular season, the Falcons reached the NFC Championship Game. Against the 15-1 Minnesota Vikings, Atlanta won a dramatic 30-27 overtime decision to reach Super Bowl XXXIII.
While the Falcons came up short in a 34-19 setback against the Denver Broncos, Atlanta's first NFC title brought plenty of excitement to the city. Running back Jamal Anderson and quarterback Chris Chandler were two of the team's outstanding players in 1998.
Atlanta Falcons Tickets at the Georgia Dome
The Georgia Dome (capacity of 71,228) enables Falcons fans to enjoy all of the NFL action in a comfortable environment. The stadium has hosted two Super Bowls and a pair of NCAA Basketball Final Fours. With a capacity of over 70,000, there are plenty of seating options to explore when purchasing Atlanta Falcons tickets.
Current Stars on the 2011 Home Slate
Behind quarterback Matt Ryan, running back Michael Turner, wide receiver Roddy White and defensive end John Abraham, the Atlanta Falcons are poised to be a title contender again in 2011. This year, the New Orleans Saints, Green Bay Packers and Philadelphia Eagles will take on the Falcons in marquee affairs at the Georgia Dome. Atlanta Falcons tickets will also be available for home games against the Tampa Bay Buccaneers, Carolina Panthers, Minnesota Vikings, Jacksonville Jaguars and Tennessee Titans. Under successful head coach Mike Smith, the Falcons will be poised to give the fans some more good times.
About the Author
GoodSeatTickets.com is a premier source for Atlanta Falcons tickets. Through our dedication to providing stellar customer service and rock-bottom discount ticket pricing, we have enjoyed tremendous success and customer satisfaction
Deion Sanders Tribute - Primetime | HD
Stadium Stars
Stadium Stars
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Tampa Bay Rays vs Boston Red Sox Online - Can the Rays Win In Their Home Stadium Today? by Richard Tyler
If you want to know about today's game between the Rays and the Red Sox, we will tell you. Here, we will break down the Red Sox vs the Rays game and let you know who will win.
As a start, let's take a look at the where and the when. The Rays versus Boston MLB game will occur at Tropicana Field on June 15th. If you want to watch this MLB matchup, you can do so easily over the Internet. To view live streams of the content, visit this link:
According to their win-loss record, Boston should take home the victory today. Their record currently stands at 39 - 27 which they'll look to improve today. The Rays will also look to improve their current record of 36 - 31 but they'll have their hands full with Boston in this outing.
We all know in the MLB anything can happen. That is why they play the game after all. Every day is a fresh start.
But now, let's take a look at specifics and see how these teams rank in against others in the MLB.
Watch Rays versus Sox online here.
With their record of 36 - 31, the Rays should not win this game against the Sox. But why not? Well, for one reason, the Tampa Bay Rays will have a tough time stopping Adrian Gonzalez and David Ortiz who lead the Boston Sox in runs batted in this year. You know that Jeremy Hellickson of the Rays will pitch to them very carefully.
But how will today's contest pan out? Will the Tampa Bay Rays be able to take down the Red Sox on their home field? Or, will the road team, the Boston Red Sox, get the win tonight? Great questions but they can only be resolved in the game. If you cannot make it to the game at Tropicana Field or catch it on television, be sure to tune into the Rays-Red Sox game at:
Watch Boston versus Rays online here.
I would like to see this contest at Tropicana Field today but I can't make it. So, to check out David Ortiz, Adrian Gonzalez, Johnny Damon, Matt Joyce and all the other stars, I will watch the Red Sox vs Rays online so I can keep up with my favorite teams and baseball stars.
Keywords: watch MLB online Wednesday, June 15th, watch Tampa Bay Rays vs Boston Red Sox online live, Tropicana Field
About the Author
To read more, swing on by our watch the MLB online website where you can watch MLB games online and get all of the latest MLB statistics.
Star Spangled Banner / National Anthem - Vanderbilt Stadium by 8yo Dominique Baseball 2011
Edition Nib
Edition Nib
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Cheap penny auctions by Joesph Legrean
Are you looking for superb deals online? If this is the case you may turn to eBay.com or Craigslist.org. These web sites have great costs on a wide range of new and used items, including pictures, books, cars, clothes, computer games, furniture, home decor, and more. If you aren't an avid Internet user, one of the issues you can run into is Internet acronyms.
You may ask why a Craigslist or eBay seller can't just type out what they need to say. Honestly, it has to do with our modern use of language. This is with the use of abbreviations. Many have grown so used to using them that they don't dare think twice.
Even if you are not a zealous net user, some popular acronyms that sellers use are easy to guess. Sadly, others are much tougher. If you see abbreviations in a Craigslist or eBay listing and you don't know what it implies, contact the vendor for more info. You can also keep on reading on for a catalogue of common abbreviations found on classified web sites and online penny penny auctions websites, as well as their meanings.
DOA means dead on arrival. This phrase is used to describe items that do not work. You are purchasing it and will receive it broken.
Both are used to describe items that are used, but in good condition. In this instance, always ask for photos, as we all have different perspectives on'like new.'
NWT means new with tags. This is most commonly associated with clothes with the tags still attached. Boxed items can be related to NIB, that means new in box. On the other hand, you'll find NWOT or NWOB to describe items that are new without the original tags or boxes.
HTF means difficult to find. LTD means restricted edition. OOP means out of print, which is for books.
You are much more likely to run into acronyms on eBay. now at least you have some idea of what can be expected.
Check out these websites:
Penny auctions - what to look for
Earn big at penny auctions
My boss left me a note or should I say "Odred"?
My boss left me a note or should I say "Odred"?
About the Author
My work as a journalist is still minimal and my focus is on random things. I have went to school at Virginia Tech and am still trying to get back in. You know what they say, once you get out of school and take a break it's really hard to start. .
Thomas and Friends Wooden Railway Collection Part 2
Mlb Action Figure
Mlb Action Figure
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Tips For Wagering On Major League Baseball - Part 1 by Nicky Michael
Major League Baseball is somewhat of an enigma. Especially when attempting to use statistics to predict a game's outcome. Even so, there is a lot of data and trends to consider before throwing one's hands up in utter frustration in baseball's defiance of probability. With patience and due diligence, a pattern may emerge. But then a gut feeling comes on and the urge to take the long shot is strong, especially when the pay out is big! The mountain of data, trends and statistics are enough to drive the sanest of us away from the bookmakers, relegating us to the sidelines. However, no one wants to live a life that boring. You can play the game - wager some cash - and make your life a whole lot more exciting.
First off, here are a few ideas to keep your sanity. These are my "top 10 baseball wagering tips for the hopelessly clueless," of which, when it comes to wagering, I am a charter member. If you consider yourself a knowledgeable bettor, these tips will still help you keep your perspective.
1) Don't bet any more than you can afford to lose.
2) Don't ever bet more to recoup a loss.
3) Ignore your gut feelings and/or hunches.
4) If a bet looks too good to be true, it probably is.
5) Once you've made your bet, remember that no amount of stress will change the outcome of a game.
6) Never risk more than 5% of your bankroll on any given game.
7) Don't bet long shots. They are long shots for a reason.
If you are on a losing streak, take a break from wagering.
9) Don't hold grudges over losses- your favorite team won't be much fun to watch if you do.
10) Target long-term goals instead of random or short-term gains.
If you follow these 10 tips then you will be head and shoulders above the average Joe who is placing bets. Of course, you must first understand what you are doing when you wager. Here are some betting basics.
A straight bet is merely betting to win or lose. Sometimes you may not be able to get such a wager without giving or taking points. This is known as the point spread. To win you must "beat the spread", or win by more than a particular team is favored by doing so. This is also known as a form of handicapping. Money lines are pretty simple; it is the amount you need to risk to win $100. So if you see a number in a column marked ML, perhaps -110, you know you need to put up $110 to win $100 and get your $110 back. So if you win, your total payout is $210. The minus sign indicates that team is the favorite. A plus sign in front of the money line indicates the underdog. With over/unders, you are wagering on the total runs that will be scored in the game. You either bet on the number being under or over that total. Action Points refer to that fact that you are betting one team against another. With action points you ignore the starting pitchers, but if there is a change in one or both of the starters, the wager or the payout could be adjusted. Side bets are just what they sound like. You can put side bets on top of your bets. With head to head propositions or match bets you are wagering on one sports figure/team beating another sports figure/team. You can also Buy Points on a handicapped or point spread contest. Usually a straight buy of 1/2 point will cost you $10 on an 11/10 (risk $110 to win $100) standard bet. A straight buy of 1 point would cost $20. If you win, you'll get back what you wagered plus $100. Sports books generally make 10% vigorish, or juice on a typical head to head straight wager. They only make it if you lose your bet.
Sports books will provide information in a compact format. The listing includes the MLB teams and pitchers with the away or visiting team and pitcher listed first and then the home team and pitcher listed underneath. The MLB money line tells you which team is the favorite (- sign) and what you must wager to win a particular amount. The MLB run line is the run differential that the sports book predicts. To win your wager, you have to beat the run line spread. The amount you wager is determined by the money line odds, located right next to the run line spread. Primarily the starting pitchers determine the money line odds. If a run line handicap is +1.5, the bet can still be won if your team loses the game, but only if they lose by one run. If they lose by two runs, you lose your wager. Run lines are always based on the listed pitchers. If the starting pitchers are changed before the game begins, these numbers may also change. The over/under will be a number in the O/U column. If the number were 7, then you would win the wager if the total number of combined runs were 8 or more. A winning under wager would result if 6 runs or less were scored.
All of this may seem rudimentary, but it's the important foundation for MLB betting. Wagering can be as simple or as complicated as you make it. There are some more complex forms of wagering that are beyond the scope of this article. In Major League Baseball Wagering - Part II, we will discuss explanations and strategies of wagering on MLB futures, parlays, multiples, round robins and teasers. We will also discuss the advantages, bonuses, safety and security of choosing a good online sports book site for wagering on MLB.
About the Author
To read about hydrangea care and violet facts, visit the Knowledge Bin website.
MLB action figure collection
Louis Cardinals Starting
Louis Cardinals Starting
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 1989 Terry Pendleton Starting Lineup SLU Sports Figurine StLouis Cardinals US $89.99
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 Starting Lineup 1999 Edition MLB Mark McGwire US $11.95
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 1999 Mark McGwire Stadium Stars SLU mint in pkg US $19.99
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 Pedro Guerrero 1988 SLU Rookie LA Dodgers Uniform NEW US $11.95
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The Arizona Cardinals Preparing For A Huge Comeback by Abel Lawson
A team in the National Football league that is one of the most watched in the league is the Arizona Cardinals. The team has been making a name for themselves not only in Arizona but in the entire United states as well. The team was started in 1898 making the Cardinals the oldest professional American football club in the United States. The team was originally situated in Chicago. The team moved to St Louis Missouri in 1960 to 1987. The team moved to Arizona in 1988 to prevent the confusion with the baseball team St Louis Cardinals. The supporters of the team continued to show their support despite the many migration the Cardinals made in the past. As the team moved from state to state, they acquired more patrons for the Cardinals Tickets.
The team has won two league championships already. They got these while still playing in Chicago. These games were won before the years of the Super Bowl. However, the team has made 8 appearances in the playoffs already. The Cardinal tickets to such games are easily sold out. Six Division championship titles has also been won by the team.
There is something special associated with the Cardinals tickets.This holds true especially for the home opener games of the team. Due to the arid condition in Arizona, the heat can sometime become too much to handle. This forced the team to play their first few weeks on the road. The earliest time they can play in their home stadium would be on the third week in the season. Most often the home opener of the team would be scheduled on the Sunday night or even the Monday night games.
Since 2006, the team has been playing in the University of Phoenix Stadium. Before the move, the team used to play their games at the Sun Devil stadium of the Arizona State University. The new stadium is able to accommodate more eager fans of the team. The facilities of the stadium are also an improvement on their former home. The location of the University of Phoenix Stadium is also more accessible to the public.
The fans of the Cardinals have been showing their unwavering support for the team. They have noticed and appreciated the improvements the team has been showcasing in the past years. A championship win is near in the horizon for the Arizona Cardinals. And rest assured that as the team wins their first Super Bowl title, the fans would be there to cheer them along the way.
About the Author
Abel Lawson is a freelance writer. He widely writes for sports especially football. He prides himself in finding cheap Cardinal tickets online. He agrees that the best Cardinals tickets are found at http://www.azcardinalstickets.com
St. Louis Cardinals Opening Day Starting Lineup
Bonds Giants
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FADING GIANTS---The Tendency for Recognized Leaders to "Lose It" as Mega Builders by Eileen Silva
Copyright 2006 Dr. Eileen Silva
It was a rare moment in networking history: four people with high MLM visibility sat together around one table. One was the man who revolutionized the diet industry, exploding his company to over 300 million within 4 years of its launch and building dozens of million-dollar earners in his 30-year tenure in the MLM industry.
On his left was another legend of MLM--- heir to one of the largest MLM fortunes to ever be amassed and owner of the company that was, arguably, the most charismatic and wealthy meteoric-rise-to-riches ever to hit our industry. My husband, Taylor Hegan, and I, who have made in excess of three million dollars the last few years, as well as creating over a dozen other millionaires in the last decade, rounded out the circle.
When the subject of industry leaders' ability to repeat their successes as they move from one company to another came up, we collectively decided that very few "big" leaders are able to change companies and repeat their track records.
Perhaps the most compelling reason for this is the nature of the dream we sell: "Build an empire that you can manage from the beaches of the world." "Create financial freedom, which gives you the time freedom to spend with your family and your hobbies."
We, who have actively helped mold the industry for the last three decades, have noticed that those who hit the big incomes seldom continue to build and work the business aggressively from a recruitment and growth emphasis after their checks surpass $20,000 a month. In light of that sabotage phenomena, I thought it would be useful to offer up some guidelines to help you avoid becoming a statistic once you hit it big!
I suggest that you: 1. Hire a staff to help you run your business like a business; 2. Never abandon doing the leadership steps that got you there. These include: retailing, advertising, sponsoring, mentoring, training, personal development work, leadership management, daily communication, and event planning. With the current trend in compensation payouts and telecommunication systems, as well as recruiting systems, distributors tend to develop their loyalty to their products and company. One of the biggest money earners of all time recently made this interesting statement: "If I wanted to leave my company today (after more than a decade and $35 million commissions earned), I wouldn't be able to move people with me. They are all so product-bonded that it's not about me, or the lure of an opportunity; it's about the results they are creating through retailing systems and new recruiting systems."
In your less successful days I would encourage you to sponsor your weakness --- in other words--- if you don't like doing mail order, I would encourage you to sponsor someone who did. As you progress up the ladder of success with MLM, let me implore you to hire your weaknesses--- so that within your immediate direction, your office continues to execute all the necessary phases of the business.
Let me also suggest that at the very least you plug back in 10% of your income toward business expenses.... and quite possibly it would be appropriate to invest considerably more than that. Taylor and I spend many thousands per month on expenses, but as he is quick to point out that we have steadily amassed a fortune in the face of this expanded tab.
If you want to avoid becoming a fading giant, you must continuously assess your business developments and surround yourself with a mastermind group that will stimulate you to be the best you can be. Remember: the true great leaders of MLM are not necessarily the biggest earners; they are the most well- rounded performers with industry staying power. Make sure, as you take your career to the superstar level, that you remember the importance of continuing to execute the tasks that originally got you there! You will then be, as multi-millionaire, Charles Givens, has always said, "Ten feet tall and bulletproof."
About the Author
Eileen Silva, Ph.D., N.D. is a metabolic health balancing expert, talk show guest, and lecturer. Dr. Silva is also an individual, group, and corporate weight management consultant. Contact Dr. Silva at http://www.dreileensilva.com
SF Giants: Beyond Barry Bonds
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Paramyotonia congenita by jekky
Symptoms and signs Patients typically complain of muscle stiffness that can continue to focal weakness This muscle stiffness cannot be walked off in contrast to myotonia congenita These symptoms are increased and sometimes induced in cold environments For example some patients have reported that eating ice cream leads to a stiffening of the throat For other patients exercise consistently induces symptoms of myotonia and or weakness Typical presentations of this are during squating or repetitive fist clenching Some patients also indicate that specific foods are able to induce symptoms of paramyotonia congenita Isolated cases have reported that carrots and watermelon are able to induce these symptoms The canonical definition of this disorder precludes permanent weakness in the definition of this disorder In practice however this has not been strictly adhered to in the literature Diagnosis Diagnosis of paramyotonia congenita is made upon evaluation of patient symptoms and case history Myotonia must increase with exercise movement and usually must worsen in cold temperatures Patients that present with permanent weakness are normally not characterized as having PC Electromyography may be used to distinguish between paramyotonia congenita and myotonia congenita Clinicians may also attempt to provoke episodes or myotonia and weakness paralysis in patients in order to determine whether the patient has PC hyperkalemic periodic paralysis or one of the potassium aggravated myotonias Genomic sequencing of the SCN4A gene is the definitive diagnostic determinant Pathophysiology Paramyotonia congenita as well as hyperkalemic periodic paralysis and the potassium aggravated myotonias is caused by mutations in a sodium channel SCN4A The phenotype of patients with these mutations is indicated in Table 1 These mutations affect fast inactivation of the encoded sodium channel There are also indications that some mutations lead to altered activation and deactivation The result of these alterations in channel kinetics is that there is prolonged inward depolarizing current following muscle excitation There is also the introduction of a indow current due to changes in the voltage sensitivity of the channel kinetics These lead to a general increase in cellular excitability as shown in figure 1 Figure 1 Theoretical simulation of a muscle membrane potential in response to 150ms depolarizing pulse of 45pA A Normal muscle produces only a single action potential due to such stimulus This is due to inactivation of sodium channels preventing their further activation even during depolarization B Myotonic muscle however is hyperexcitable and able to produce action potentials for the duration of the stimulus pulse This model adapted from Cannon 1993 There has been one study of a large number of patients with paramyotonia congenita Of 26 kindreds it found that 17 71 had a mutation in SCN4A while 6 29 had no known mutation There is no large difference between these two groups except that patients with no known mutation have attacks precipitated less by cold but more by hunger are much more likely to have normal muscle biopsies and show less decreased compound muscle action potentials when compared to patients with known mutations Table 1 Summary of mutations found in patients diagnosed with paramyotonia congenita and their resulting phenotypes Mutation Region Myotonia Weakness References Cold Exercise Activity Potassium Cold Exercise Activity Potassium R672C D2S4 I693T D2S4 S5 N Y Y Y T704M D2S5 Y Y Y Y S804F D2S6 Y Y Y Y N A1152D D3S4 S5 Y A1156T D3S4 S5 Y Y V1293I D3S4 Y Y N N G1306V D3 4 Y Y Y Y T1313A D3 4 Y Y N Y Y N T1313M D3 4 Y Y N Y Y N M1360V D4S1 Y Y M1370V D4S1 Y Y N N N Y L1433R D4S3 Y Y Y Y N R1448C D4S4 Y Y N N Y N R1448H D4S4 Y Y Y Y Y R1448P D4S4 Y Y Y N R1448S D4S4 Y Y N Y N R1456E D4S4 Y Y N N N N V1458F D4S4 F1473S D4S4 S5 M1592V D4S6 Y Y Y Y Y Y E1702K C term N N F1795I C term Y Symptoms of both PC and hyperKPP Periodica paralytica paramyotonica Also diagnosed as a Potassium aggravated myotonia Original case reports unpublished When exercised in a cold environment After muscles were cooled This table was adapted from Vicart et al 2005 Cold refers to symptoms either occurring or significantly worsening with cold temperatures Likewise Exercise Activity refers to symptom onset or severity worsening with exercise and or more general movement like hand clenching Potassium refers to ingestion of food high in potassium or other disorders which are known to increase serum potassium levels Mutation region nomenclature is domain number e g D1 followed by segment number e g S4 Thus D2S3 indicates that the mutation is in the 3rd membrane spanning loop of the 2nd domain Some mutations occur between segments and are denoted similarly e g D4S4 S5 occurs between the 4th and 5th segments of the 4th domain Other mutations are located between domains and are denoted DX Y where X and Y are domain numbers C term refers to the carboxy terminus Treatment Management Some patients do not require treatment to manage the symptoms of paramyotonia congenita Others however require treatment for their muscle stiffness and often find mexiletine to be helpful Others have found acetazolamide to be helpful as well Avoidance of myotonia triggering events is also an effective method of mytonia prevention Epidemiology Paramyotonia congenita is considered an extremely rare disorder though little epidemiological work has been done Prevalence is generally higher in European derived populations and lower among Asians Epidemiological estimates have been provided for the German population Here it was estimated that the prevalence of PC is between 1 350 000 0 00028 and 1 180 000 0 00056 It should be noted however that the German population of patients with PC is not uniformly distributed across the country Many individuals with PC herald from the Ravensberg area in North West Germany where a founder effect is seems to be responsible for most cases The prevalence here is estimated at 1 6000 or 0 017 History Originally thought to be separate from hyperkalemic periodic paralysis and the sodium channel myotonias there is now considerable disagreement as to whether these disorders represent separate entities or overlapping phenotypes of a complex disorder spectrum External links Paramyotonia congenita FAQ at the Periodic Paralysis News Desk The site also hosts a mailing list for patients with the disorder and medical professionals interested in it Fact page from the Muscular Dystrophy Association Notes Lehmann Horn F Rdel R Ricker K 1993 Non dystrophic myotonias and periodic paralyses A European Neuromuscular Center Workshop held 4 6 October 1992 Ulm Germany Neuromuscul Disord 3 2 1618 doi 10 1016 0960 8966 93 90009 9 PMID 7689382 Cannon S 2006 Pathomechanisms in channelopathies of skeletal muscle and brain Annu Rev Neurosci 29 387415 doi 10 1146 annurev neuro 29 051605 112815 PMID 16776591 References Facts About Myopathies MDA Publications Eulenburg A 1886 ber eine familire durch 6 Generationen verfolgbare Form kongenitaler Paramyotonie Neurol Zentralbl 12 265 72 a b de Silva S Kuncl R Griffin J Cornblath D Chavoustie S 1990 Paramyotonia congenita or hyperkalemic periodic paralysis Clinical and electrophysiological features of each entity in one family Muscle Nerve 13 1 216 doi 10 1002 mus 880130106 PMID 2325698 Subramony S Malhotra C Mishra S 1983 Distinguishing paramyotonia congenita and myotonia congenita by electromyography Muscle Nerve 6 5 3749 doi 10 1002 mus 880060506 PMID 6888415 Streib E 1984 Evoked response testing in myotonic syndromes Muscle Nerve 7 7 5902 PMID 6544373 Cannon S Brown R Corey D 1993 Theoretical reconstruction of myotonia and paralysis caused by incomplete inactivation of sodium channels Biophys J 65 1 27088 doi 10 1016 S0006 3495 93 81045 2 PMID 8396455 a b c Miller T Dias da Silva M Miller H Kwiecinski H Mendell J Tawil R McManis P Griggs R Angelini C Servidei S Petajan J Dalakas M Ranum L Fu Y Ptcek L 2004 Correlating phenotype and genotype in the periodic paralyses Neurology 63 9 164755 PMID 15534250 a b Plassart E Eymard B Maurs L Hauw J Lyon Caen O Fardeau M Fontaine B 1996 Paramyotonia congenita genotype to phenotype correlations in two families and report of a new mutation in the sodium channel gene J Neurol Sci 142 1 2 12633 doi 10 1016 0022 510X 96 00173 6 PMID 8902732 Ptcek L George A Griggs R Tawil R Kallen R Barchi R Robertson M Leppert M 1991 Identification of a mutation in the gene causing hyperkalemic periodic paralysis Cell 67 5 10217 doi 10 1016 0092 8674 91 90374 8 PMID 1659948 Kim J Hahn Y Sohn E Lee Y Yun J Kim J Chung J 2001 Phenotypic variation of a Thr704Met mutation in skeletal sodium channel gene in a family with paralysis periodica paramyotonica J Neurol Neurosurg Psychiatry 70 5 61823 doi 10 1136 jnnp 70 5 618 PMID 11309455 Brancati F Valente E Davies N Sarkozy A Sweeney M LoMonaco M Pizzuti A Hanna M Dallapiccola B 2003 Severe infantile hyperkalaemic periodic paralysis and paramyotonia congenita broadening the clinical spectrum associated with the T704M mutation in SCN4A J Neurol Neurosurg Psychiatry 74 9 133941 doi 10 1136 jnnp 74 9 1339 PMID 12933953 a b c d Ptek L Tawil R Griggs R Meola G McManis P Barohn R Mendell J Harris C Spitzer R Santiago F 1994 Sodium channel mutations in acetazolamide responsive myotonia congenita paramyotonia congenita and hyperkalemic periodic paralysis Neurology 44 8 15003 PMID 8058156 a b McClatchey A McKenna Yasek D Cros D Worthen H Kuncl R DeSilva S Cornblath D Gusella J Brown R 1992 Novel mutations in families with unusual and variable disorders of the skeletal muscle sodium channel Nat Genet 2 2 14852 doi 10 1038 ng1092 148 PMID 1338909 Bouhours M Luce S Sternberg D Willer J Fontaine B Tabti N 2005 A1152D mutation of the Na channel causes paramyotonia congenita and emphasizes the role of DIII S4 S5 linker in fast inactivation J Physiol 565 Pt 2 41527 doi 10 1113 jphysiol 2004 081018 PMID 15790667 a b McClatchey A Van den Bergh P Pericak Vance M Raskind W Verellen C McKenna Yasek D Rao K Haines J Bird T Brown R 1992 Temperature sensitive mutations in the III IV cytoplasmic loop region of the skeletal muscle sodium channel gene in paramyotonia congenita Cell 68 4 76974 doi 10 1016 0092 8674 92 90151 2 PMID 1310898 Lerche H Heine R Pika U George A Mitrovic N Browatzki M Weiss T Rivet Bastide M Franke C Lomonaco M Human sodium channel myotonia slowed channel inactivation due to substitutions for a glycine within the III IV linker J Physiol 470 1322 PMID 8308722 Bouhours M Sternberg D Davoine C Ferrer X Willer J Fontaine B Tabti N 2004 Functional characterization and cold sensitivity of T1313A a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humans J Physiol 554 Pt 3 63547 doi 10 1113 jphysiol 2003 053082 PMID 14617673 a b c d Ptacek L Gouw L Kwieciski H McManis P Mendell J Barohn R George A Barchi R Robertson M Leppert M 1993 Sodium channel mutations in paramyotonia congenita and hyperkalemic periodic paralysis Ann Neurol 33 3 3007 doi 10 1002 ana 410330312 PMID 8388676 Wagner S Lerche H Mitrovic N Heine R George A Lehmann Horn F 1997 A novel sodium channel mutation causing a hyperkalemic paralytic and paramyotonic syndrome with variable clinical expressivity Neurology 49 4 101825 PMID 9339683 Okuda S Kanda F Nishimoto K Sasaki R Chihara K 2001 Hyperkalemic periodic paralysis and paramyotonia congenita a novel sodium channel mutation J Neurol 248 11 10034 doi 10 1007 s004150170059 PMID 11757950 a b Ptcek L George A Barchi R Griggs R Riggs J Robertson M Leppert M 1992 Mutations in an S4 segment of the adult skeletal muscle sodium channel cause paramyotonia congenita Neuron 8 5 8917 doi 10 1016 0896 6273 92 90203 P PMID 1316765 a b c d Meyer Kleine C Otto M Zoll B Koch M 1994 Molecular and genetic characterization of German families with paramyotonia congenita and demonstration of founder effect in the Ravensberg families Hum Genet 93 6 70710 doi 10 1007 BF00201577 PMID 8005599 Lerche H Mitrovic N Dubowitz V Lehmann Horn F 1996 Paramyotonia congenita the R1448P Na channel mutation in adult human skeletal muscle Ann Neurol 39 5 599608 doi 10 1002 ana 410390509 PMID 8619545 Bendahhou S Cummins T Kwiecinski H Waxman S Ptcek L Characterization of a new sodium channel mutation at arginine 1448 associated with moderate Paramyotonia congenita in humans J Physiol 518 Pt 2 33744 PMID 10381583 Sasaki R Takano H Kamakura K Kaida K Hirata A Saito M Tanaka H Kuzuhara S Tsuji S 1999 A novel mutation in the gene for the adult skeletal muscle sodium channel alpha subunit SCN4A that causes paramyotonia congenita of von Eulenburg Arch Neurol 56 6 6926 doi 10 1001 archneur 56 6 692 PMID 10369308 a b Lehmann Horn F Rdel R Ricker K 1993 Non dystrophic myotonias and periodic paralyses A European Neuromuscular Center Workshop held 4 6 October 1992 Ulm Germany Neuromuscul Disord 3 2 1618 doi 10 1016 0960 8966 93 90009 9 PMID 7689382 Lehmann Horn F Rdel R Ricker K Lorkovi H Dengler R Hopf H 1983 Two cases of adynamia episodica hereditaria in vitro investigation of muscle cell membrane and contraction parameters Muscle Nerve 6 2 11321 doi 10 1002 mus 880060206 PMID 6304507 Fontaine B Khurana T Hoffman E Bruns G Haines J Trofatter J Hanson M Rich J McFarlane H Yasek D 1990 Hyperkalemic periodic paralysis and the adult muscle sodium channel alpha subunit gene Science 250 4983 10002 doi 10 1126 science 2173143 PMID 2173143 Rojas C Wang J Schwartz L Hoffman E Powell B Brown R 1991 A Met to Val mutation in the skeletal muscle Na channel alpha subunit in hyperkalaemic periodic paralysis Nature 354 6352 3879 doi 10 1038 354387a0 PMID 1659668 Heine R Pika U Lehmann Horn F 1993 A novel SCN4A mutation causing myotonia aggravated by cold and potassium Hum Mol Genet 2 9 134953 doi 10 1093 hmg 2 9 1349 PMID 8242056 Kelly P Yang W Costigan D Farrell M Murphy S Hardiman O 1997 Paramyotonia congenita and hyperkalemi
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I am an expert from China Crafts Suppliers, usually analyzes all kind of industries situation, such as ceramic transfer paper , diabetic cookbook.
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